Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia

Gizachew Gobebo; Alemayehu Siffir; Belema Hailu; Birhanu Woldeyohannes; Bizunesh Kefale; Temesgen Senbeto; Adinew Handiso; O. Chandrasekhara Reddy

doi:doi:10.11648/j.sjcm.20211003.11

Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia

Gizachew Gobebo, Alemayehu Siffir, Belema Hailu, Birhanu Woldeyohannes, Bizunesh Kefale, Temesgen Senbeto, Adinew Handiso, O. Chandrasekhara Reddy

Published in Science Journal of Clinical Medicine (Volume 10, Issue 3)

Received: 31 July 2021 Accepted: 16 August 2021 Published: 24 August 2021

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Abstract

Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.

Published in	Science Journal of Clinical Medicine (Volume 10, Issue 3)
DOI	10.11648/j.sjcm.20211003.11
Page(s)	72-77
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Mortality, HIV, Binary Logistic Regression Model

References

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[11]	Lawn, S. D., Little, F., Bekker, L. G., Kaplan, R., Campbel, E., Orrell, C., & Wood, R. (2009). Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa. AIDS (London, England), 23 (3), 335.
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APA Style

Gizachew Gobebo, Alemayehu Siffir, Belema Hailu, Birhanu Woldeyohannes, Bizunesh Kefale, et al. (2021). Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia. Science Journal of Clinical Medicine, 10(3), 72-77. https://doi.org/10.11648/j.sjcm.20211003.11

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Gizachew Gobebo; Alemayehu Siffir; Belema Hailu; Birhanu Woldeyohannes; Bizunesh Kefale, et al. Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia. Sci. J. Clin. Med. 2021, 10(3), 72-77. doi: 10.11648/j.sjcm.20211003.11

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AMA Style

Gizachew Gobebo, Alemayehu Siffir, Belema Hailu, Birhanu Woldeyohannes, Bizunesh Kefale, et al. Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia. Sci J Clin Med. 2021;10(3):72-77. doi: 10.11648/j.sjcm.20211003.11

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@article{10.11648/j.sjcm.20211003.11,
  author = {Gizachew Gobebo and Alemayehu Siffir and Belema Hailu and Birhanu Woldeyohannes and Bizunesh Kefale and Temesgen Senbeto and Adinew Handiso and O. Chandrasekhara Reddy},
  title = {Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia},
  journal = {Science Journal of Clinical Medicine},
  volume = {10},
  number = {3},
  pages = {72-77},
  doi = {10.11648/j.sjcm.20211003.11},
  url = {https://doi.org/10.11648/j.sjcm.20211003.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20211003.11},
  abstract = {Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.},
 year = {2021}
}

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TY  - JOUR
T1  - Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia
AU  - Gizachew Gobebo
AU  - Alemayehu Siffir
AU  - Belema Hailu
AU  - Birhanu Woldeyohannes
AU  - Bizunesh Kefale
AU  - Temesgen Senbeto
AU  - Adinew Handiso
AU  - O. Chandrasekhara Reddy
Y1  - 2021/08/24
PY  - 2021
N1  - https://doi.org/10.11648/j.sjcm.20211003.11
DO  - 10.11648/j.sjcm.20211003.11
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 72
EP  - 77
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20211003.11
AB  - Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.
VL  - 10
IS  - 3
ER  -

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Author Information

Gizachew Gobebo

Department of Statistics, Ambo University, Ambo, Ethiopia
Alemayehu Siffir

Department of Statistics, Ambo University, Ambo, Ethiopia
Belema Hailu

Department of Statistics, Ambo University, Ambo, Ethiopia
Birhanu Woldeyohannes

Technical and Financial Capacity Building Department, Addis Ababa Transport Bureau, Addis Ababa, Ethiopia
Bizunesh Kefale

Department of Statistics, Ambo University, Ambo, Ethiopia
Temesgen Senbeto

Department of Statistics, Ambo University, Ambo, Ethiopia
Adinew Handiso

Department of Statistics, Wachamo University, Durame, Ethiopia
O. Chandrasekhara Reddy

Department of Statistics, Eritrean Institute of Technology, Asmara, Eritrea

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APA Style

Gizachew Gobebo, Alemayehu Siffir, Belema Hailu, Birhanu Woldeyohannes, Bizunesh Kefale, et al. (2021). Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia. Science Journal of Clinical Medicine, 10(3), 72-77. https://doi.org/10.11648/j.sjcm.20211003.11

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ACS Style

Gizachew Gobebo; Alemayehu Siffir; Belema Hailu; Birhanu Woldeyohannes; Bizunesh Kefale, et al. Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia. Sci. J. Clin. Med. 2021, 10(3), 72-77. doi: 10.11648/j.sjcm.20211003.11

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AMA Style

Gizachew Gobebo, Alemayehu Siffir, Belema Hailu, Birhanu Woldeyohannes, Bizunesh Kefale, et al. Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia. Sci J Clin Med. 2021;10(3):72-77. doi: 10.11648/j.sjcm.20211003.11

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@article{10.11648/j.sjcm.20211003.11,
  author = {Gizachew Gobebo and Alemayehu Siffir and Belema Hailu and Birhanu Woldeyohannes and Bizunesh Kefale and Temesgen Senbeto and Adinew Handiso and O. Chandrasekhara Reddy},
  title = {Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia},
  journal = {Science Journal of Clinical Medicine},
  volume = {10},
  number = {3},
  pages = {72-77},
  doi = {10.11648/j.sjcm.20211003.11},
  url = {https://doi.org/10.11648/j.sjcm.20211003.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20211003.11},
  abstract = {Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Influencing Factors of Mortality Among Adult HIV Patients Under Antiretroviral Therapy: The Case of Hossana Queen Elleni Mohammad Memorial Hospital, Ethiopia
AU  - Gizachew Gobebo
AU  - Alemayehu Siffir
AU  - Belema Hailu
AU  - Birhanu Woldeyohannes
AU  - Bizunesh Kefale
AU  - Temesgen Senbeto
AU  - Adinew Handiso
AU  - O. Chandrasekhara Reddy
Y1  - 2021/08/24
PY  - 2021
N1  - https://doi.org/10.11648/j.sjcm.20211003.11
DO  - 10.11648/j.sjcm.20211003.11
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 72
EP  - 77
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20211003.11
AB  - Even though the use of ART has brought a significant reduction in the mortality and morbidity of patients living with HIV/AIDS globally, still a number of patients die after the start of Antiretroviral Therapy. This study aimed at identifying influencing factors of mortality among adult HIV infected patients who are on ART in Hossana Queen Elleni Mohammad Memorial Hospital. The data for the study were obtained from Hossana Queen Elleni Mohammad Memorial Hospital Antiretroviral Therapy clinic. The HIV infected patients ≥ 15 years of age. Binary logistic regression model was applied to analyze the data so as to identify the influencing factors associated with mortality of HIV infected patients. A total of 400 adult HIV infected patients who were under ART were included in the study. Of 400 patients, 18.75% of them died. Age of the patients 40 or above (OR=1.73, 95% CI: 1.13–1.92), primary education (OR=0.29, 95% CI: 0.030–0.71), secondary or above education (OR=0.13, 95% CI: 0.03–0.16), alcohol (OR=3.35, 95% CI: 1.79– 6.27), baseline weight 50 kg or above (OR=0.42, 95% CI: 0.23–0.77), TB positive (OR=3.76, 95% CI: 2.06–6.83), and baseline CD4 200 or above (OR=0.24, 95% CI: 0.19–0.50) were significantly associated with mortality among HIV patients under Antiretroviral Therapy. Health workers need to support those patients with no or little education by continuous awareness creation of taking care of themselves and knowing what factors facilitate death. Furthermore, patients who drink alcohol need to reduce excessive drinking.
VL  - 10
IS  - 3
ER  -

Copy | Download